The sheer scale of the disaster facing the planet shocked those involved in the research.
They estimate that more than 1 million species will be lost by 2050. The results are described as "terrifying" by Chris Thomas, professor of conservation biology at Leeds University, who is lead author of the research from four continents published today in the magazine Nature.
Much of that loss-more than one in 10 of all plants and animals-is already irreversible because of the extra global warming gases already discharged into the atmosphere.
But the scientists say that action to curb greenhouse gases now could save many more from the same fate.
The research in Europe, Australia, Central and South America, and South Africa, showed that species living in mountainous areas had a greater chance of survival because they could simply move uphill to get cooler.
Those in flatter areas such as Brazil, Mexico and Australia, were more vulnerable, faced with the impossible task of moving thousands of miles to find suitable conditions.
The survey studied global warming links to 1 103 species of plants, mammals, birds, reptiles, frogs and insects in South Africa, Brazil, Europe, Australia, Mexico and Costa Rica and extrapolated findings as far as 2050.
It did not examine the oceans.
The researchers concede there are many uncertainties in both climate forecasts and the computer models they used to forecast future extinctions. But they said their dire conclusions may well come to pass if industrial nations do not curtail emissions of greenhouse gases.
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